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Mouse Ercc1 activation kit by CRISPRa

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SKU
GA201285
Ercc1 CRISPRa kit - CRISPR gene activation of mouse excision repair cross-complementing rodent repair deficiency, complementation group 1
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ercc1
Locus ID 13870
Components

GA201285G1, Ercc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201285G2, Ercc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201285G3, Ercc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001127324, NM_007948
UniProt ID P07903
Synonyms Ercc-1
Summary Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4 (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN505321 Ercc1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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