Mouse Efnb3 activation kit by CRISPRa

SKU
GA201195
Efnb3 CRISPRa kit - CRISPR gene activation of mouse ephrin B3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Efnb3
Locus ID 13643
Components

GA201195G1, Efnb3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA201195G2, Efnb3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA201195G3, Efnb3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_007911
UniProt ID O35393
Synonyms EFL-6; ELF-3; Elk-L3; Epl8; LERK-8; NLERK-2
Summary Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN505048 Efnb3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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