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Mouse Ctsl activation kit by CRISPRa

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SKU
GA200953
Ctsl CRISPRa kit - CRISPR gene activation of mouse cathepsin L
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Ctsl
Locus ID 13039
Components

GA200953G1, Ctsl gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200953G2, Ctsl gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200953G3, Ctsl gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_009984
UniProt ID P06797
Synonyms 1190035F06Rik; CatL; Ctsl1; fs; MEP; nkt
Summary This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the activation peptide and the cathepsin L1 heavy and light chains. The mature enzyme appears to be important in embryonic development through its processing of histone H3 and may play a role in disease progression in a model of kidney disease. Homozygous knockout mice for this gene exhibit hair loss, skin thickening, bone and heart defects, and enhanced susceptibility to bacterial infection. A pseudogene of this gene has been identified in the genome. provided by RefSeq, Aug 2015
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Documents
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Other Versions
SKU Description Size Price
KN503993 Ctsl - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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