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Mouse Abcc2 activation kit by CRISPRa

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SKU
GA200781
Abcc2 CRISPRa kit - CRISPR gene activation of mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 2
  $1,657.00
4 Weeks*

Other products for "Abcc2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Abcc2
Locus ID 12780
Components

GA200781G1, Abcc2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200781G2, Abcc2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200781G3, Abcc2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_013806
UniProt ID Q8VI47
Synonyms Abc30; AI173996; Cmoat; cMRP; Mrp2
Summary The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the canalicular surface of the hepatocyte and in biliary transport, and appears to contribute to drug resistance in mammalian cells. Several different mutations in the human gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. Alternative splice variants have been observed for this gene; however, they have not been fully described. provided by RefSeq, Jul 2008
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Documents
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Other Versions
SKU Description Size Price
KN500624 Abcc2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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