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Mouse Bckdhb activation kit by CRISPRa

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SKU
GA200379
Bckdhb CRISPRa kit - CRISPR gene activation of mouse branched chain ketoacid dehydrogenase E1, beta polypeptide
  $1,657.00
4 Weeks*

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Bckdhb
Locus ID 12040
Components

GA200379G1, Bckdhb gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200379G2, Bckdhb gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200379G3, Bckdhb gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_199195
UniProt ID Q6P3A8
Synonyms BCKDE1B; BCKDH E1-beta
Summary This gene encodes the beta chain of the branched chain alpha ketoacid dehydrogenase (Bckdh) complex. The encoded protein exists in a heterotetrameric complex containing the Bckdh alpha subunit to form the E1 catalytic component of Bckdh complex. The Bckdh complex catalyzes the oxidative decarboxylation of branched chain ketoacids to their corresponding acyl-CoA esters, during the catabolism of leucine, isoleucine and valine. In humans, certain mutations in this gene cause maple syrup urine disease. Alternative splicing results in multiple transcript variants encoding different isoforms. A pseudogene for this gene has been identified. provided by RefSeq, Apr 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN502091 Bckdhb - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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