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Mouse Apoc3 activation kit by CRISPRa

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SKU
GA200243
Apoc3 CRISPRa kit - CRISPR gene activation of mouse apolipoprotein C-III
  $1,657.00
4 Weeks*

Other products for "Apoc3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Apoc3
Locus ID 11814
Components

GA200243G1, Apoc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200243G2, Apoc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200243G3, Apoc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001289755, NM_001289756, NM_001289833, NM_023114
UniProt ID P33622
Synonyms apo-CIII; apoC-III
Summary This gene encodes an apolipoprotein which is the major protein component of very-low-density lipoproteins (VLDL) and a minor component of high-density lipoproteins (HDL). The encoded protein is thought to regulate the metabolism of triglyceride-rich lipoproteins and play a role in lipid storage and the mobilization of fat cells. This gene is clustered with three other apolipoprotein genes on chromosome 9 and is associated with coronary disease. Mice lacking this gene have lower levels of total cholesterol in the plasma. Mutations in the human genes causes hyperalphalipoproteinemia 2, a disorder of lipid metabolism which results in a favorable lipid profile (lower LDL-cholesterol, higher HDL-cholesterol and lower levels of serum triglycerides when fasting and after a meal). Alternative splicing results in multiple transcript variants. provided by RefSeq, Jan 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN501418 Apoc3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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