Human UPK3B activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | UPK3B |
| Locus ID | 105375355 |
| Components |
GA119713G1, UPK3B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA119713G2, UPK3B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA119713G3, UPK3B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_030570, NM_182683, NM_182684, NM_001347684 |
| UniProt ID | Q9BT76 |
| Synonyms | P35; UP3B; UPIIIB |
| Summary | UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 PubMed 12446744).supplied by OMIM, Mar 2008 |
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