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Human CCDC61 activation kit by CRISPRa

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SKU
GA119009
CCDC61 CRISPRa kit - CRISPR gene activation of human coiled-coil domain containing 61
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA374344 CCDC61 Rabbit polyclonal Antibody
100 ul
$410.00
RC220143 CCDC61 (Myc-DDK-tagged)-Human coiled-coil domain containing 61 (CCDC61)
10 ug
$494.00

Other products for "CCDC61"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CCDC61
Locus ID 729440
Components

GA119009G1, CCDC61 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA119009G2, CCDC61 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA119009G3, CCDC61 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001080402, NM_001267723
UniProt ID Q9Y6R9
Synonyms coiled-coil domain containing 61
Summary Microtubule-binding centrosomal protein required for centriole cohesion, independently of the centrosome-associated protein/CEP250 and rootletin/CROCC linker (PubMed:31789463). In interphase, required for anchoring microtubule at the mother centriole subdistal appendages and for centrosome positioning (PubMed:31789463). During mitosis, may be involved in spindle assembly and chromatin alignment by regulating the organization of spindle microtubules into a symmetrical structure (PubMed:30354798). Has been proposed to play a role in CEP170 recruitment to centrosomes (PubMed:30354798). However, this function could not be confirmed (PubMed:31789463). Plays a non-essential role in ciliogenesis (PubMed:31789463, PubMed:32375023).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN420143 CCDC61 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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