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Human TEX19 activation kit by CRISPRa

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SKU
GA118275
TEX19 CRISPRa kit - CRISPR gene activation of human testis expressed 19
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA335110 Rabbit polyclonal Anti-FLJ35767 Antibody
100 ul
$585.00
RC209297 TEX19 (Myc-DDK-tagged)-Human testis expressed 19 (TEX19)
10 ug
$289.00

Other products for "TEX19"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TEX19
Locus ID 400629
Components

GA118275G1, TEX19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA118275G2, TEX19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA118275G3, TEX19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_207459
UniProt ID Q8NA77
Synonyms FLJ35767
Summary Required during spermatogenesis and placenta development, participating in the repression of retrotransposable elements and prevent their mobilization. Collaborates with the Piwi-interacting RNA (piRNA) pathway, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins. Interacts with Piwi proteins and directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Also during spermatogenesis, promotes, with UBR2, SPO11-dependent recombination foci to accumulate and drive robust homologous chromosome synapsis (By similarity). Interacts with LINE-1 retrotransposon encoded LIRE1, stimulates LIRE1 polyubiquitination, mediated by UBR2, and degradation, inhibiting LINE-1 retranstoposon mobilization (PubMed:28806172).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN409297 TEX19 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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