Human MUC21 activation kit by CRISPRa

SKU
GA118239
MUC21 CRISPRa kit - CRISPR gene activation of human mucin 21, cell surface associated
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MUC21
Locus ID 394263
Components

GA118239G1, MUC21 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA118239G2, MUC21 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA118239G3, MUC21 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001010909, NR_130720, NM_001322370, NM_001322371
UniProt ID Q5SSG8
Synonyms C6orf205; KMQK697; MUC-21
Summary This gene encodes a large membrane-bound glycoprotein which is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. The encoded protein contains an N-terminal signal sequence, an extracellular mucin domain, a stem domain, a transmembrane domain, and a C-terminal cytoplasmic tail domain. The mucin domain contains O-glycosylation sites and is polymorphic with isoforms containing a variable number of nonidentical proline-, threonine-, and serine-rich tandem repeats of 15 amino acids each. The aberrent expression of this gene is associated with lung adenocarcinoma. provided by RefSeq, May 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN415917 MUC21 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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