Human IYD activation kit by CRISPRa

SKU
GA118056
IYD CRISPRa kit - CRISPR gene activation of human iodotyrosine deiodinase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol IYD
Locus ID 389434
Components

GA118056G1, IYD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA118056G2, IYD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA118056G3, IYD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001164694, NM_001164695, NM_001318495, NM_203395, NR_134655
UniProt ID Q6PHW0
Synonyms C6orf71; DEHAL1; IYD-1; TDH4
Summary This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants. provided by RefSeq, Sep 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN408896 IYD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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