Human THEMIS activation kit by CRISPRa

SKU GA117886

THEMIS CRISPRa kit - CRISPR gene activation of human thymocyte selection associated

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: THEMIS
• Locus ID: 387357
• Components:

  GA117886G1, THEMIS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117886G2, THEMIS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117886G3, THEMIS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001010923, NM_001164685, NM_001164687, NM_001318531
• UniProt ID: Q8N1K5
• Synonyms: C6orf190; C6orf207; GASP; SPOT; TSEPA
• Summary: This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]