Human HSD11B1L activation kit by CRISPRa

SKU GA117783

HSD11B1L CRISPRa kit - CRISPR gene activation of human hydroxysteroid 11-beta dehydrogenase 1 like

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: HSD11B1L
• Locus ID: 374875
• Components:

  GA117783G1, HSD11B1L gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA117783G2, HSD11B1L gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA117783G3, HSD11B1L gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001267868, NM_001267869, NM_001267870, NM_001267871, NM_198533, NM_198704, NM_198705, NM_198706, NM_198707, NM_198708
• UniProt ID: Q7Z5J1
• Synonyms: 11-beta-HSD3; 11-DH3; HSD3; SCDR10; SCDR10B; SDR26C2
• Summary: This gene is a member of the hydroxysteroid dehydrogenase family. The encoded protein is similar to an enzyme that catalyzes the interconversion of inactive to active glucocorticoids (e.g. cortisone). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jun 2012]