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Human GEN1 activation kit by CRISPRa

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SKU
GA117684
GEN1 CRISPRa kit - CRISPR gene activation of human GEN1 Holliday junction 5' flap endonuclease
  $1,657.00
4 Weeks*

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Other products for "GEN1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol GEN1
Locus ID 348654
Components

GA117684G1, GEN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA117684G2, GEN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA117684G3, GEN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001130009, NM_182625
UniProt ID Q17RS7
Synonyms Gen
Summary This gene encodes a member of the Rad2/xeroderma pigmentosum group G nuclease family, whose members are characterized by N-terminal and internal xeroderma pigmentosum group G nuclease domains followed by helix-hairpin-helix domains and disordered C-terminal domains. The protein encoded by this gene is involved in resolution of Holliday junctions, which are intermediate four-way structures that covalently link DNA during homologous recombination and double-strand break repair. The protein resolves Holliday junctions by creating dual incisions across the junction to produce nicked duplex products that can be ligated. In addition, this protein has been found to localize to centrosomes where it has been implicated in regulation of centrosome integrity. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2016
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Other Versions
SKU Description Size Price
KN421451 GEN1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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