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Human RAB43 activation kit by CRISPRa

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SKU
GA117400
RAB43 CRISPRa kit - CRISPR gene activation of human RAB43, member RAS oncogene family
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA358956 RAB43 Antibody - C-terminal region
100 ul
$585.00
RC209159 RAB43 (Myc-DDK-tagged)-Human RAB43, member RAS oncogene family (RAB43), transcript variant 1
10 ug
$300.00

Other products for "RAB43"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol RAB43
Locus ID 339122
Components

GA117400G1, RAB43 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA117400G2, RAB43 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA117400G3, RAB43 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001204883, NM_001204884, NM_001204885, NM_001204886, NM_001204887, NM_001204888, NM_198490
UniProt ID Q86YS6
Synonyms RAB11B; RAB41
Summary The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN409159 RAB43 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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