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Human PNPLA1 activation kit by CRISPRa

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SKU
GA117260
PNPLA1 CRISPRa kit - CRISPR gene activation of human patatin like phospholipase domain containing 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA330996 Rabbit polyclonal Anti-PNPLA1 Antibody
100 ul
$585.00
RC218871 PNPLA1 (Myc-DDK-tagged)-Human patatin-like phospholipase domain containing 1 (PNPLA1), transcript variant 1
10 ug
$457.00

Other products for "PNPLA1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PNPLA1
Locus ID 285848
Components

GA117260G1, PNPLA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA117260G2, PNPLA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA117260G3, PNPLA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001039725, NM_001145716, NM_001145717, NM_173676
UniProt ID Q8N8W4
Synonyms ARCI10; dJ50J22.1
Summary The protein encoded by this gene belongs to the patatin-like phospholipase (PNPLA) family, which is characterized by the presence of a highly conserved patatin domain. PNPLA family members have diverse lipolytic and acyltransferase activities, and are key elements in lipid metabolism. While other members of this family have been well characterized, the function of this gene remained an enigma. However, recent studies show that this gene is expressed in the skin epidermal keratinocytes, and has a role in glycerophospholipid metabolism in the cutaneous barrier. Consistent with these observations, mutations in this gene are associated with ichthyosis in human (autosomal recessive congenital ichthyoses, ARCI) and dog. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Jun 2012
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Documents
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Other Versions
SKU Description Size Price
KN418871 PNPLA1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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