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Human KCTD21 activation kit by CRISPRa

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SKU
GA116999
KCTD21 CRISPRa kit - CRISPR gene activation of human potassium channel tetramerization domain containing 21
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA384589 KCTD21 Rabbit monoclonal Antibody
100 ul
$380.00
RC206177 KCTD21 (Myc-DDK-tagged)-Human potassium channel tetramerisation domain containing 21 (KCTD21)
10 ug
$300.00

Other products for "KCTD21"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol KCTD21
Locus ID 283219
Components

GA116999G1, KCTD21 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116999G2, KCTD21 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116999G3, KCTD21 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001029859
UniProt ID Q4G0X4
Synonyms KCASH2
Summary Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN406177 KCTD21 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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