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Human ZNF683 activation kit by CRISPRa

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SKU
GA116885
ZNF683 CRISPRa kit - CRISPR gene activation of human zinc finger protein 683
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA341518 Rabbit Polyclonal Anti-ZNF683 Antibody
100 ul
$525.00
RC225865 ZNF683 (Myc-DDK-tagged)-Human zinc finger protein 683 (ZNF683), transcript variant 1
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$289.00 $469.00

Other products for "ZNF683"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ZNF683
Locus ID 257101
Components

GA116885G1, ZNF683 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116885G2, ZNF683 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116885G3, ZNF683 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001114759, NM_001307925, NM_173574
UniProt ID Q8IZ20
Synonyms Hobit
Summary Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T-cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Plays also a role in the differentiation of both thymic and peripheral NKT cells. Negatively regulates the accumulation of interferon-gamma (IFN-gamma) in NKT cells at steady state or after antigenic stimulation. Positively regulates granzyme B production in NKT cells after innate stimulation. Associates with the transcriptional repressor PRDM1/BLIMP1 to chromatin at gene promoter regions.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN406157 ZNF683 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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