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Human MCOLN2 activation kit by CRISPRa

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SKU
GA116814
MCOLN2 CRISPRa kit - CRISPR gene activation of human mucolipin 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MCOLN2
Locus ID 255231
Components

GA116814G1, MCOLN2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116814G2, MCOLN2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116814G3, MCOLN2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_153259, NM_001330647
UniProt ID Q8IZK6
Synonyms TRP-ML2; TRPML2
Summary Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 PubMed 17662026).supplied by OMIM, Sep 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN411195 MCOLN2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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