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Human SPDYA activation kit by CRISPRa

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SKU
GA116694
SPDYA CRISPRa kit - CRISPR gene activation of human speedy/RINGO cell cycle regulator family member A
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC210559 SPDYA (Myc-DDK-tagged)-Human speedy homolog A (Xenopus laevis) (SPDYA), transcript variant 1
10 ug
$300.00

Other products for "SPDYA"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SPDYA
Locus ID 245711
Components

GA116694G1, SPDYA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116694G2, SPDYA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116694G3, SPDYA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001008779, NM_001142634, NM_182756
UniProt ID Q5MJ70
Synonyms RINGO3; RINGOA; SPDY1; SPY1
Summary Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1 and CDK2 (PubMed:12972555). Contributes to CDK2 activation without promoting CDK2 phosphorylation, by inducing a conformation change of the CDK2 T-loop that obstructs the substrate-binding cleft prior to kinase activation (PubMed:28666995). Mediates cell survival during the DNA damage process through activation of CDK2 (PubMed:12839962).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN410559 SPDYA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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