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Human DAND5 activation kit by CRISPRa

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SKU
GA116310
DAND5 CRISPRa kit - CRISPR gene activation of human DAN domain BMP antagonist family member 5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA503555 DAND5 mouse monoclonal antibody, clone OTI2H3 (formerly 2H3) 100 ul
$447.00
RC221703 DAND5 (Myc-DDK-tagged)-Human DAN domain family, member 5 (DAND5)
10 ug
$300.00

Other products for "DAND5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DAND5
Locus ID 199699
Components

GA116310G1, DAND5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116310G2, DAND5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116310G3, DAND5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_152654
UniProt ID Q8N907
Synonyms CER2; CERL2; CKTSF1B3; COCO; CRL2; DANTE; GREM3; SP1
Summary This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN421703 DAND5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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