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Human COL22A1 activation kit by CRISPRa

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SKU
GA116182
COL22A1 CRISPRa kit - CRISPR gene activation of human collagen type XXII alpha 1 chain
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC220741 COL22A1 (Myc-DDK-tagged)-Human collagen, type XXII, alpha 1 (COL22A1)
10 ug
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Other products for "COL22A1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol COL22A1
Locus ID 169044
Components

GA116182G1, COL22A1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116182G2, COL22A1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116182G3, COL22A1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_152888
UniProt ID Q8NFW1
Synonyms collagen, type XXII, alpha 1
Summary This gene encodes member of the collagen family which is thought to contribute to the stabilization of myotendinous junctions and strengthen skeletal muscle attachments during contractile activity. It belongs to the fibril-associated collagens with interrupted triple helix (FACIT) subset of the collagen superfamily, which associate with collagen fibers through their C-terminal collagenous domains and mediate protein-protein interactions through their N-terminal noncollagenous domains. The encoded protein is deposited in the basement membrane zone of the myotendinous junction which is present only at the tissue junctions of muscles, tendons, the heart, articular cartilage, and skin. A knockdown of the orthologous zebrafish gene induces a muscular dystrophy by disruption of the myotendinous junction. provided by RefSeq, May 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN420741 COL22A1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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