OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human DENND1B activation kit by CRISPRa

Be the first to review this product
SKU
GA116090
DENND1B CRISPRa kit - CRISPR gene activation of human DENN domain containing 1B
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA365750 DENND1B rabbit polyclonal antibody
100 ul
$310.00
RC205585 DENND1B (Myc-DDK-tagged)-Human DENN/MADD domain containing 1B (DENND1B), transcript variant 2
10 ug
$457.00

Other products for "DENND1B"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DENND1B
Locus ID 163486
Components

GA116090G1, DENND1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA116090G2, DENND1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA116090G3, DENND1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001142795, NM_001195215, NM_001195216, NM_001300858, NM_144977, NR_125340
UniProt ID Q6P3S1
Synonyms C1orf218; DENN/MADD domain containing 1B; DKFZp547O0715; FAM31B; family with sequence similarity 31, member B; FLJ20054; FLJ21179; FLJ33888; MGC27044; MGC103810; RP11-53I24.2
Summary Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 PubMed 20154091).supplied by OMIM, Nov 2010
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN405585 DENND1B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products