Human DENND5B activation kit by CRISPRa

SKU GA116005

DENND5B CRISPRa kit - CRISPR gene activation of human DENN domain containing 5B

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: DENND5B
• Locus ID: 160518
• Components:

  GA116005G1, DENND5B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA116005G2, DENND5B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA116005G3, DENND5B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_144973, NM_001308339, NM_001366890, NM_001366891, NM_001366892, NM_001366893
• UniProt ID: Q6ZUT9
• Synonyms: DKFZp686P1174; FLJ41648; FLJ43333; MGC24039
• Summary: Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.[UniProtKB/Swiss-Prot Function]