Human TTLL11 activation kit by CRISPRa

SKU GA115948

TTLL11 CRISPRa kit - CRISPR gene activation of human tubulin tyrosine ligase like 11

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TTLL11
• Locus ID: 158135
• Components:

  GA115948G1, TTLL11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115948G2, TTLL11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115948G3, TTLL11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001139442, NM_194252
• UniProt ID: Q8NHH1
• Synonyms: bA244O19.1; C9orf20
• Summary: Polyglutamase which preferentially modifies alpha-tubulin. Involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step (By similarity). Required for CCSAP localization to both spindle and cilia microtubules (PubMed:22493317). Generates long side-chains (By similarity).[UniProtKB/Swiss-Prot Function]