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Human STARD6 activation kit by CRISPRa

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SKU
GA115603
STARD6 CRISPRa kit - CRISPR gene activation of human StAR related lipid transfer domain containing 6
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA337906 Rabbit Polyclonal Anti-STARD6 Antibody
100 ul
$585.00
RC223175 STARD6 (Myc-DDK-tagged)-Human StAR-related lipid transfer (START) domain containing 6 (STARD6)
10 ug
$300.00

Other products for "STARD6"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol STARD6
Locus ID 147323
Components

GA115603G1, STARD6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115603G2, STARD6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115603G3, STARD6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_139171, NR_138549
UniProt ID P59095
Synonyms OTTHUMP00000163555; StAR-related lipid transfer (START) domain containing 6; START domain containing 6; START domain containing protein 6
Summary Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD6 (Soccio et al., 2002 PubMed 12011452).supplied by OMIM, Mar 2008
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Documents
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Other Versions
SKU Description Size Price
KN423175 STARD6 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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