Human SUHW2 (ZNF280B) activation kit by CRISPRa

SKU
GA115427
ZNF280B CRISPRa kit - CRISPR gene activation of human zinc finger protein 280B
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ZNF280B
Locus ID 140883
Components

GA115427G1, SUHW2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115427G2, SUHW2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115427G3, SUHW2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_080764, NR_130642, NR_130643
UniProt ID Q86YH2
Synonyms 5 OY11.1; D87009.C22.3; SUHW2; ZNF279; ZNF632
Summary The protein encoded by this gene is a transcription factor that upregulates expression of MDM2, which negatively regulates p53 expression. This gene is highly expressed in prostate cancer cells, which leads to a reduction in p53 levels and an increase in growth of the cancer cells. Several transcript variants have been found for this gene, but only one of them is protein-coding. provided by RefSeq, Jan 2015
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Documents
Resources
Other Versions
SKU Description Size Price
KN408088 ZNF280B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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