Human LCN8 activation kit by CRISPRa

SKU GA115306

LCN8 CRISPRa kit - CRISPR gene activation of human lipocalin 8

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: LCN8
• Locus ID: 138307
• Components:

  GA115306G1, LCN8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115306G2, LCN8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115306G3, LCN8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001345934, NM_178469
• UniProt ID: Q6JVE9
• Synonyms: EP17; LCN5
• Summary: Members of the lipocalin family, such as LCN8, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]