Human LSM11 activation kit by CRISPRa

SKU GA115223

LSM11 CRISPRa kit - CRISPR gene activation of human LSM11, U7 small nuclear RNA associated

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: LSM11
• Locus ID: 134353
• Components:

  GA115223G1, LSM11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA115223G2, LSM11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA115223G3, LSM11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_173491
• UniProt ID: P83369
• Synonyms: FLJ38273
• Summary: Component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing (By similarity). Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to the Sm-binding site of U7 snRNA.[UniProtKB/Swiss-Prot Function]