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Human OTOP1 activation kit by CRISPRa

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SKU
GA115193
OTOP1 CRISPRa kit - CRISPR gene activation of human otopetrin 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC221713 OTOP1 (Myc-DDK-tagged)-Human otopetrin 1 (OTOP1)
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Other products for "OTOP1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol OTOP1
Locus ID 133060
Components

GA115193G1, OTOP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA115193G2, OTOP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA115193G3, OTOP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_177998
UniProt ID Q7RTM1
Synonyms MGC163302; MGC163304
Summary This gene encodes a transmembrane protein which belongs to the otopetrin domain protein family and is required for the formation of otoconia and otoliths, calcium carbonate biominerals within the inner ear of mammals that are required for the detection of linear acceleration and gravity. This gene modulates purinergic control of intracellular calcium in vestibular supporting cells. Naturally occurring mutations in the orthologous mouse gene are associated with nonsyndromic otoconia agenesis and a consequent balance defect. The orthologous mouse gene is also induced in white adipose tissue during obesity. The encoded protein is a component of a counterinflammatory pathway that attenuates obesity-induced adipose tissue inflammation and plays an adaptive role in maintaining metabolic homeostasis in obesity. provided by RefSeq, Jul 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN421713 OTOP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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