Human DNAI3 activation kit by CRISPRa

SKU
GA114966
WDR63 CRISPRa kit - CRISPR gene activation of human WD repeat domain 63
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol DNAI3
Locus ID 126820
Components

GA114966G1, DNAI3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114966G2, DNAI3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114966G3, DNAI3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001288563, NM_145172
UniProt ID Q8IWG1
Synonyms DIC3; NYD-SP29
Summary Acts as a negative regulator of cell migration, invasion, and metastasis downstream of p53/TP53, through inhibition of Arp2/3 complex-mediated actin polymerization (PubMed:32128961). Via its association with the multisubunit axonemal dynein complex, is potentially involved in the regulation of cilia function (By similarity). May play a role in osteogenesis of dental tissue-derived mesenchymal stem cells (By similarity).UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN406699 WDR63 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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