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Human LRRC25 activation kit by CRISPRa

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SKU
GA114939
LRRC25 CRISPRa kit - CRISPR gene activation of human leucine rich repeat containing 25
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA504883 LRRC25 mouse monoclonal antibody, clone OTI1D9 (formerly 1D9) 100 ul
$447.00
RC209911L4V Lenti ORF particles, LRRC25 (mGFP-tagged) - Human leucine rich repeat containing 25 (LRRC25), 200ul, >10^7 TU/mL
200 ul
$850.00

Other products for "LRRC25"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LRRC25
Locus ID 126364
Components

GA114939G1, LRRC25 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114939G2, LRRC25 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114939G3, LRRC25 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_145256
UniProt ID Q8N386
Synonyms MAPA
Summary Plays a role in the inhibition of RLR-mediated type I interferon signaling pathway by targeting DDX58/RIG-I for autophagic degradation. Interacts specifically with ISG15-associated DDX58 to promote interaction between DDX58 and the autophagic cargo receptor p62/SQSTM1 to mediate DDX58 degradation via selective autophagy (PubMed:29288164). Plays also a role in the inhibition of NF-kappa-B signaling pathway and inflammatory response by promoting the degradation of p65/RELA.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN409911 LRRC25 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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