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Human MRPL10 activation kit by CRISPRa

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SKU
GA114878
MRPL10 CRISPRa kit - CRISPR gene activation of human mitochondrial ribosomal protein L10
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA808643 MRPL10 mouse monoclonal antibody, clone OTI2B4 (formerly 2B4) 100 ul
$447.00
RC208608 MRPL10 (Myc-DDK-tagged)-Human mitochondrial ribosomal protein L10 (MRPL10), nuclear gene encoding mitochondrial protein, transcript variant 1
10 ug
$300.00

Other products for "MRPL10"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MRPL10
Locus ID 124995
Components

GA114878G1, MRPL10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114878G2, MRPL10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114878G3, MRPL10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_145255, NM_148887, NR_037575
UniProt ID Q7Z7H8
Synonyms L10MT; MRP-L8; MRP-L10; MRPL8; RPML8
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. provided by RefSeq, Nov 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN408608 MRPL10 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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