Human TARS3 activation kit by CRISPRa

SKU GA114807

TARSL2 CRISPRa kit - CRISPR gene activation of human threonyl-tRNA synthetase like 2

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: TARS3
• Locus ID: 123283
• Components:

  GA114807G1, TARS3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA114807G2, TARS3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA114807G3, TARS3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_152334
• UniProt ID: A2RTX5
• Synonyms: FLJ25005
• Summary: Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage.[UniProtKB/Swiss-Prot Function]