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Human TOP1MT activation kit by CRISPRa

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SKU
GA114595
TOP1MT CRISPRa kit - CRISPR gene activation of human DNA topoisomerase I mitochondrial
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA324243 Anti-TOP1MT Rabbit Polyclonal Antibody
100 ul
$305.00
RC208637 TOP1MT (Myc-DDK-tagged)-Human topoisomerase (DNA) I, mitochondrial (TOP1MT), nuclear gene encoding mitochondrial protein
10 ug
$559.00

Other products for "TOP1MT"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TOP1MT
Locus ID 116447
Components

GA114595G1, TOP1MT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114595G2, TOP1MT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114595G3, TOP1MT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001258446, NM_001258447, NM_052963
UniProt ID Q969P6
Summary This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, May 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN408637 TOP1MT - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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