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Human ACPL2 (PXYLP1) activation kit by CRISPRa

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SKU
GA114213
PXYLP1 CRISPRa kit - CRISPR gene activation of human 2-phosphoxylose phosphatase 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC213267 ACPL2 (Myc-DDK-tagged)-Human acid phosphatase-like 2 (ACPL2), transcript variant 2
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Other products for "PXYLP1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PXYLP1
Locus ID 92370
Components

GA114213G1, ACPL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA114213G2, ACPL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA114213G3, ACPL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001037172, NM_001282728, NM_152282
UniProt ID Q8TE99
Synonyms ACPL2; HEL124; XYLP
Summary Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1-4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN407863 ACPL2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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