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Human TSLP activation kit by CRISPRa

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SKU
GA113910
TSLP CRISPRa kit - CRISPR gene activation of human thymic stromal lymphopoietin
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA364572 TSLP rabbit polyclonal antibody
100 ul
$310.00
RC214101 TSLP (Myc-DDK-tagged)-Human thymic stromal lymphopoietin (TSLP), transcript variant 1
10 ug
$150.00

Other products for "TSLP"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TSLP
Locus ID 85480
Components

GA113910G1, TSLP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113910G2, TSLP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113910G3, TSLP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_033035, NM_138551, NR_033425, NR_045089
UniProt ID Q969D9
Synonyms thymic stromal lymphopoietin
Summary This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. In addition, the shorter (predominant) isoform is an antimicrobial protein, displaying antibacterial and antifungal activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, Jul 2020
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Documents
Resources
Other Versions
SKU Description Size Price
KN407348 TSLP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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