Human TRIM5 alpha (TRIM5) activation kit by CRISPRa

SKU
GA113859
TRIM5 CRISPRa kit - CRISPR gene activation of human tripartite motif containing 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TRIM5
Locus ID 85363
Components

GA113859G1, TRIM5 alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113859G2, TRIM5 alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113859G3, TRIM5 alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_033034, NM_033092, NM_033093
UniProt ID Q9C035
Synonyms RNF88; TRIM5alpha
Summary The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq, Dec 2009
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Documents
Resources
Other Versions
SKU Description Size Price
KN405696 TRIM5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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