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Human LINGO1 activation kit by CRISPRa

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SKU
GA113746
LINGO1 CRISPRa kit - CRISPR gene activation of human leucine rich repeat and Ig domain containing 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC203867 LINGO1 (Myc-DDK-tagged)-Human leucine rich repeat and Ig domain containing 1 (LINGO1)
10 ug
$865.00

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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol LINGO1
Locus ID 84894
Components

GA113746G1, LINGO1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113746G2, LINGO1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113746G3, LINGO1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001301186, NM_001301187, NM_001301189, NM_001301191, NM_001301192, NM_001301194, NM_001301195, NM_001301197, NM_001301198, NM_001301199, NM_001301200, NM_032808
UniProt ID Q96FE5
Synonyms LERN1; LRRN6A; UNQ201
Summary Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN403867 LINGO1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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