Human CEP78 activation kit by CRISPRa

SKU
GA113383
CEP78 CRISPRa kit - CRISPR gene activation of human centrosomal protein 78
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CEP78
Locus ID 84131
Components

GA113383G1, CEP78 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113383G2, CEP78 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113383G3, CEP78 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001098802, NM_032171, NM_001330691, NM_001330693, NM_001330694, NM_001349838, NM_001349839, NM_001349840
UniProt ID Q5JTW2
Synonyms C9orf81; IP63
Summary This gene encodes a centrosomal protein that is both required for the regulation of centrosome-related events during the cell cycle, and required for ciliogenesis. The encoded protein has an N-terminal leucine-rich repeat (LRR) domain with six consecutive LRR repeats, and a C-terminal coiled-coil domain. It interacts with the N-terminal catalytic domain of polo-like kinase 4 (PLK4) and colocalizes with PLK4 to the distal end of the centriole. Naturally occurring mutations in this gene cause defects in primary cilia that result in retinal degeneration and sensorineural hearing loss which are associated with cone-rod degeneration disease as well as Usher syndrome. Low expression of this gene is associated with poor prognosis of colorectal cancer patients. provided by RefSeq, Mar 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN417621 CEP78 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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