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Human TMEM49 (VMP1) activation kit by CRISPRa

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SKU
GA113107
VMP1 CRISPRa kit - CRISPR gene activation of human vacuole membrane protein 1
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC202623 VMP1 (Myc-DDK-tagged)-Human vacuole membrane protein 1 (VMP1)
10 ug
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol VMP1
Locus ID 81671
Components

GA113107G1, TMEM49 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113107G2, TMEM49 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113107G3, TMEM49 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001329394, NM_001329395, NM_001329396, NM_001329397, NM_001329398, NM_001329399, NM_001329400, NM_001329401, NM_001329402, NM_030938
UniProt ID Q96GC9
Synonyms EPG3; TANGO5; TMEM49
Summary This gene encodes a transmembrane protein that plays a key regulatory role in the process of autophagy. The ectopic overexpression of the encoded protein in cultured cells triggers autophagy even under nutrient-rich conditions. This gene is overexpressed in pancreatitis affected acinar cells where the encoded protein mediates sequestration and degradation of potentially deleterious activated zymogen granules in a process termed, zymophagy. provided by RefSeq, Jul 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN402623 VMP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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