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Human PVRL4 (NECTIN4) activation kit by CRISPRa

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SKU
GA113085
NECTIN4 CRISPRa kit - CRISPR gene activation of human nectin cell adhesion molecule 4
  $1,657.00
4 Weeks*

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Other products for "NECTIN4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NECTIN4
Locus ID 81607
Components

GA113085G1, PVRL4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA113085G2, PVRL4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA113085G3, PVRL4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_030916
UniProt ID Q96NY8
Synonyms EDSS1; LNIR; nectin-4; PRR4; PVRL4
Summary This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.provided by RefSeq, Jan 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN403431 PVRL4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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