Human HSD3B7 activation kit by CRISPRa

SKU
GA112898
HSD3B7 CRISPRa kit - CRISPR gene activation of human hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HSD3B7
Locus ID 80270
Components

GA112898G1, HSD3B7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112898G2, HSD3B7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112898G3, HSD3B7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001142777, NM_001142778, NM_025193
UniProt ID Q9H2F3
Synonyms CBAS1; PFIC4; SDR11E3
Summary This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, Dec 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN402468 HSD3B7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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