Human L2HGDH activation kit by CRISPRa

SKU
GA112746
L2HGDH CRISPRa kit - CRISPR gene activation of human L-2-hydroxyglutarate dehydrogenase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol L2HGDH
Locus ID 79944
Components

GA112746G1, L2HGDH gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112746G2, L2HGDH gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112746G3, L2HGDH gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_024884
UniProt ID Q9H9P8
Synonyms C14orf160; L2HGA
Summary This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe cognitive disability. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN417631 L2HGDH - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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