Human ZNF408 activation kit by CRISPRa

SKU GA112632

ZNF408 CRISPRa kit - CRISPR gene activation of human zinc finger protein 408

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: ZNF408
• Locus ID: 79797
• Components:

  GA112632G1, ZNF408 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA112632G2, ZNF408 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA112632G3, ZNF408 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001184751, NM_024741
• UniProt ID: Q9H9D4
• Synonyms: FLJ12827
• Summary: The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP). [provided by RefSeq, Dec 2016]