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Human MICALL2 activation kit by CRISPRa

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SKU
GA112618
MICALL2 CRISPRa kit - CRISPR gene activation of human MICAL like 2
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC207726 MICALL2 (Myc-DDK-tagged)-Human MICAL-like 2 (MICALL2), transcript variant 1
10 ug
$589.00 $828.00

Other products for "MICALL2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MICALL2
Locus ID 79778
Components

GA112618G1, MICALL2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112618G2, MICALL2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112618G3, MICALL2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_024723, NM_182924
UniProt ID Q8IY33
Synonyms FLJ23471; FLJ23471, FLJ44858; FLJ41996; FLJ44858; FLJ45410; JRAB; junctional Rab13-binding protein; MGC46023; MICAL-L2; MICAL-like 2
Summary Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN407726 MICALL2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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