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Human TMEM108 activation kit by CRISPRa

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SKU
GA112280
TMEM108 CRISPRa kit - CRISPR gene activation of human transmembrane protein 108
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA355837 TMEM108 Antibody - middle region
100 ul
$525.00
RC200953 TMEM108 (Myc-DDK-tagged)-Human transmembrane protein 108 (TMEM108), transcript variant 1
10 ug
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Other products for "TMEM108"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TMEM108
Locus ID 66000
Components

GA112280G1, TMEM108 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112280G2, TMEM108 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112280G3, TMEM108 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001136469, NM_001282865, NM_023943
UniProt ID Q6UXF1
Synonyms CT124
Summary Transmembrane protein required for proper cognitive functions. Involved in the development of dentate gyrus (DG) neuron circuitry, is neccessary for AMPA receptors surface expression and proper excitatory postsynaptic currents of DG granule neurons. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport. Through the interaction with DST, mediates the docking of the dynein/dynactin motor complex to vesicle cargos for retrograde axonal transport. In hippocampal neurons, required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 and recruits the WAVE1 complex to facilitate actin-dependent BDNF:NTRK2 early endocytic trafficking and mediate signaling from early endosomes.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN400953 TMEM108 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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