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Human MRPS15 activation kit by CRISPRa

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SKU
GA112205
MRPS15 CRISPRa kit - CRISPR gene activation of human mitochondrial ribosomal protein S15
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA808641 MRPS15 mouse monoclonal antibody, clone OTI5F5 (formerly 5F5) 100 ul
$447.00
RC207694 MRPS15 (Myc-DDK-tagged)-Human mitochondrial ribosomal protein S15 (MRPS15), nuclear gene encoding mitochondrial protein
10 ug
$300.00

Other products for "MRPS15"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MRPS15
Locus ID 64960
Components

GA112205G1, MRPS15 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA112205G2, MRPS15 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA112205G3, MRPS15 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_031280
UniProt ID P82914
Synonyms DC37; MPR-S15; RPMS15; S15mt
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN407694 MRPS15 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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