Human LMBR1 activation kit by CRISPRa
Specifications
| Product Data | |
| Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
|---|---|
| Target Symbol | LMBR1 |
| Locus ID | 64327 |
| Components |
GA112040G1, LMBR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA112040G2, LMBR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA112040G3, LMBR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
| OTI Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_022458, NM_001350953, NM_001350954, NM_001350955, NM_001350956, NM_001350957, NM_001350958, NR_146958, NM_001363409, NM_001363410, NM_001363411, NM_001363412, NM_001363413, NR_146959 |
| UniProt ID | Q8WVP7 |
| Synonyms | ACHP; C7orf2; DIF14; LSS; PPD2; THYP; TPT; ZRS |
| Summary | This gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. provided by RefSeq, Jul 2008 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| KN403703 | LMBR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. | 1 kit |
$1,657.00
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Citations
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