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Human CRLF2 activation kit by CRISPRa

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SKU
GA111979
CRLF2 CRISPRa kit - CRISPR gene activation of human cytokine receptor like factor 2
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC221190 CRLF2 (Myc-DDK-tagged)-Human cytokine receptor-like factor 2 (CRLF2), transcript variant 1
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Other products for "CRLF2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CRLF2
Locus ID 64109
Components

GA111979G1, CRLF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA111979G2, CRLF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA111979G3, CRLF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001012288, NM_022148, NR_110830
UniProt ID Q9HC73
Synonyms CRL2; CRLF2Y; TSLPR
Summary This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. provided by RefSeq, Sep 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN421190 CRLF2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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